The keyboard features 16 LCD keys + 12 Cherry MX keys with relegendable keycaps. All of them are fully programmable in 4 layers. Each LCD key can display 32x16 pixels graphics and has its own backlight. The color of the backlight can be customized for each key. Later models support 64 backlight colors (8 colors for older models). Worth noting is that the LCD keys will not function without an external power supply!

You can connect the Chameleon to the PC using PS/2, Serial or both at the same time! According to Tipro, it's even possible to define which connection is used for specific commands, if both are connected. You can of course use it with the Blue Cube in which case you lose the ability to program the unit. However, since everything is stored in non-volatile memory, this isn't really a problem. Unfortunately for some, Tipro ChangeMe will only run under Windows.
I bought the keyboard mainly for Photoshop. To achieve this, I grabbed the icons from PS7, modified them and loaded them up into ChangeMe. Here you can see the result (1st and 2nd Layer):


Programming the unit is very straightforward and well documented.
Thanks for reading!

More info:
Tipro website - Free+ Chameleon Module